postoperative analgesia
Conditions
Interventions
Group 1:Transversus abdominis plane block with 0.9% saline
Group 2:Transversus abdominis plane block with ropivacaine
Group 3:Transversus abdominis plane block with dexmedetomi
Group 4:Transversus abdominis plane block with dexmedetomidine
Sponsors
The Second Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Adults who have open abdominal surgery
Exclusion criteria
Exclusion criteria: Age less than 18; body mass index (BMI) more than 40 kg/m2; weight less than 50kg; coagulopathy; a history of relevant drug allergy; chronic hepatic or renal insufficiency; precnancy or breastfeeding; a history of alcohol or analgesics dependence; chronic pain.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the time for TAP block;noninvasive blood pressure (NIBP) and heart rate;the concentrations of ropivacaine and dexmedetomid;duration of PACU;Median VAS pain scores while coughing and at rest;QoR40;tramadol requirements;nausea and vomiting during the first 48 postoperat;the time to return to die; | — |
Countries
China
Contacts
Public ContactWenzhi Li
Outcome results
None listed