A randomized, double-blind assessment of the sedative and analgesic effects of intranasal dexmedetomidine in nasal endoscopic surgery cases

A randomized, double-blind assessment of the sedative and analgesic effects of intranasal dexmedetom

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-14004886

Enrollment

Unknown

Registered

2014-07-02

Start date

2014-08-25

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic nasal sinusitis

Interventions

LD1 group:Nasal drops of DEX 1ug/kg 60 min before local ane

LD2 group:Nasal drops of DEX 1.5ug/kg 60 min before local an

Eligibility

Sex/Gender

Male

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Age 18 to 60 years; 2. ASA I to II; 3. BMI 18.5 to 28 kg/m2.

Exclusion criteria

Exclusion criteria: 1. Smoking; 2. Hypertension and Diabetes; 3. The central nervous system lesions; 4. History of nasal surgery; 5. Liver and kidney dysfunction; 6. Taking sedatives 2 days before operation; 7. Sinus bradycardia, the patients with emotional tension can't under local anesthesia.

Design outcomes

Primary

Measure	Time frame
BP, HR, SPO;	—

Countries

China

Contacts

Public ContactLI JUAN

huamuzi1999@126.com+86 13956005465

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026