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The effect of chromium and magnesium supplementation on glucose tolerance and metabolism of glucose and lipid in insulin resistant population

The effect of chromium (valence 3) and magnesium supplementation on glucose tolerance and metabolism

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004863
Enrollment
Unknown
Registered
2014-06-20
Start date
2011-06-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

insulin resistance

Interventions

1:control
2:chromium (valence 3) (120ug/d)
3:magnesium (200mg/d)
4:chromium (valence 3) (120ug/d)+magnesium (200mg/d)

Sponsors

Medical College of Qingdao University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 59 Years

Inclusion criteria

Inclusion criteria: 1) aged 45-59 years; 2) insulin resistance, HOM-IR more than 1; 3) agree not to smoke and drink during the trial.

Exclusion criteria

Exclusion criteria: 1) High serum magnesium, hypercalcemia, cancer, coronary heart disease; patients with active peptic ulcer; patients need to take drugs; 2) patients with active liver disease or cirrhosis, or liver dysfunction, whose serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) are 1.5 times higher than the normal range; 3) being allergic to the test nutrient, or being high sensitivity constitution; 4) alcoholics or drug addicts; 5) patients who had participated in other clinical trials three months prior to the screening for participants of this project.

Design outcomes

Primary

MeasureTime frame
fasting insulin;fasting blood glucose;PKC;apoptosis of lymphcyte;—

Countries

China

Contacts

Public ContactDou Mei

Medical College of Qingdao University

littlefeidou@163.com+86 0532-85953559

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026