Effect of oxycodone combined with dexmedetomidine for Patient-Controlled Intravenous Analgesia after VATS Lobectomy A prospective randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-14004858

Enrollment

Unknown

Registered

2014-06-26

Start date

2013-08-30

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Interventions

1:oxycodone with dexmedetomidine

2:dexmedetomidine alone

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Aged 18-75 years; height 155-180 cm; Thoracoscopic lobectomy due to lung cancer; To be able to understand verbal and written mandarin.

Exclusion criteria

Exclusion criteria: 1. Intolerable to one-lung ventilation; 2. a long history of opioid analgesic use or NSAIDS, tranquilliser use, psychiatric disorders; 3. bradycardia with cardiac conduction or rhythm abnormalities; 4. History of rib fracture, trauma or lung surgery at the same side of operation; 5. Open thoracotomy conversion; 6. Reoperation due to postoperative bleeding or others.

Design outcomes

Primary

Measure	Time frame
Visual analog score)VAS;Ramsay sedation scores;	—

Secondary

Measure	Time frame
Total oxycodone consumption;side effect;requirement for rescue analgesic;infused PCA dose;satisfaction;consumption of oxycodone;	—

Countries

China

Contacts

Public ContactXiuqin Wang

Shandong Provincial Cancer Hospital

jasmine75@163.com+86 13665416586

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026