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Pathogenesis of chronic rhinosinusitis with and without nasal polyps

Pathogenesis of chronic rhinosinusitis with and without nasal polyps

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004834
Enrollment
Unknown
Registered
2014-05-28
Start date
2013-03-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic rhinosinusitis

Interventions

chronic rhinosiusitis with nasal polyps:radical endoscopic sinus surgery
chronic rhinosinusitis without nasal polyps:medical therapy with glucocorticoid
chronic rhinosinusitis without nasal polyps:functional endoscopic sinus surgery
chronic rhinosiusitis with nasal polyps:medical therapy with glucocorticoid
control group:non

Sponsors

Beijing Tongren hospital, Capital medical university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
22 Years to 70 Years

Inclusion criteria

Inclusion criteria: patients with chronic rhinosinusitis, 18-70 years old, without uncontrolled hypertension or diabetes.

Exclusion criteria

Exclusion criteria: 1. patients with CF, Kartgener Disease, invasive and noninvasive fungal sinusitis, neoplasm,and immunodeficiency; 2. patients with acute airway infection in recent one month; 3. patients with pregnancy or lactation.

Design outcomes

Primary

MeasureTime frame
Signal pathway of TGF;cytokine of Th1 type;cytokine of Th2 typ;—

Secondary

MeasureTime frame
Treg cel;—

Countries

China

Contacts

Public ContactBing Zhou

Beijing Tongren Hospital, Capital medical University

entzhou@263.net+86 010 58269106

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026