Effect of dexmedetomidine on renal injury in patients undergoing cardiac valve replacement under cardiopulmonary bypass

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-14004832

Enrollment

Unknown

Registered

2014-06-09

Start date

2014-06-29

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the renal injury in patients undergoing cardiac valve replacement under

Interventions

control group:Injection of 0.9% saline

Experimental:dexmedetomidine

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Sixty physical status ASA II-III or NYHA physical status I-III patients of sexes, aged 20-60 years, scheduled for elective cardiac valve replacement.

Exclusion criteria

Exclusion criteria: With double beam or ? degree atrioventricular block, has a history of drug allergy, 2 weeks before and during the test using renal toxicity drugs, clear liver and renal insufficiency, moderate or more lung dysfunction, hypertension ? period, basis and diabetic kidney disease history, etc.

Design outcomes

Primary

Measure	Time frame
BUN;plasma concentration of Cr;the level of serum NGAL;the level of serum IL-18;The urine output;incidence of postoperative acute kidney injur;	—

Contacts

Public ContactLi Juan

Anhui Provincial Hospital

huamuzi1999@126.com+86 13956005465

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026