Bipolar II depressive episode
Conditions
Interventions
first group:quetiapine+false TMS treatment
second group:quetaipine+rTMS high-frequency
Third group:quetaipine+rTMS low-frequency
Sponsors
The First Affiliated Hospital, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Qutpatient and inpatient in our department; Aged 18-45 years; Meet the DSM-5 diagnostic criteria of first-episode Bipolar disorder II depressive episode; MDQ: positive, HAMD17 score:=17 points, CGIscore:=4 points.
Exclusion criteria
Exclusion criteria: Female subjects with pregnancy or in lactation; Serious physical diseases: epilepsy, myocardial infarction, unstable angina, congestive heart failure, severe liver cirrhosis, acute or chronic renal failure, severe diabetes, aplastic anemia, other serious nervous system, heart, liver, renal, endocrine, blood and other body disease; Intracranial Metal foreign body; With pacemaker; With cochlear implants; Intracranial hypertension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD;MADRS;BRMS;CG; | — |
Countries
China
Contacts
Public ContactShaohua Hu
The First Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed