intracranial space occupying lesion
Conditions
Interventions
Simply Hydromorphone:PCA with Hydromorphone ih
Hydromorphy combined with MCT:PCA with Hydromorphone ih and MCT sticked to the two side of the wound
Sponsors
Beijing Sanbo Brain Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Aged 18-65 years old, both male and female, ASA I and II, sanity patients, explicit diagnosis, selective craniotomy, estimated operation duration time < 6 hours, informed consent been signed.
Exclusion criteria
Exclusion criteria: 1. Participating in other clinical trials within four weeks; 2. Patients who suffer severe organic disease (serious liver or kidney disease, NYHA> III class, etc); 3. Major bleeding or blood pressure or heart rate fluctuate wildly in surgery; 4. The operation time>6 hour; 5. Patient with respiratory depression, airway obstruction,tissue hypoxia,history of asthma,severe intracranial hypertension, cerebral hernia and coma; 6. lactating and pregnant women; 7. Patient who would not be extubation because the surgical site close to respiratory and circular centre resulting in poor breathing recovery; 8. Idiopathic epilepsy and long-term using of AED patients; 9. Patients have psychonosema; 10. Volunteers who are using central analgesic medications. Opiate addiction, and dependence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| consumption of analgesic;healing grade; | — |
Countries
China
Contacts
Public ContactWang Baoguo
Department of Anesthesiology, Beijing Sanbo Brain Hospital, Capital Medical University
Outcome results
None listed