Infarction
Conditions
Interventions
Experimental group:For blood pressure >180/120mmHg patients, intravenous infusion nitroglycerin Oil or sodium nitroprusside and oral medicine within a week of the onset under monitoring
for SBP <180mmHg and/or DBP<120mmHg patients, oral antihypertensive medicine. 7 days after the onset, all patients oral antihypertensive drugs.
Control:In the first two weeks the participants will not be treated by antihypertention, after then will be given same treatment same as experimental group
Sponsors
Lianyungang City First People's Hospital
Eligibility
Sex/Gender
All
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. aged 35-75 years old hospitalized patients, male or female; 2. According to "all kinds of cerebrovascular disease diagnostic criteria" cerebrovascular disease diagnosis Fourth National Conference of ischemic stroke (cerebral infarction); 3. onset = 24h; 4. have a clear positioning nervous system signs, neurological deficit scores: NIHSS 4 to 24, and NIHSS fifth and sixth upper limbs and lower limbs score of = 2 points; 5. obtained legally authorized representative informed the patient or the patient signed consent.
Exclusion criteria
Exclusion criteria: 1. head CT findings of intracranial bleeding disorders: hemorrhagic stroke, epidural hematoma, intracranial hematoma, intraventricular hemorrhage, subarachnoid hemorrhage; 2. severe disturbance of consciousness: 1a level of awareness of the project NIHSS score of > 1 points; 3. the premorbid mRS score> 1 minute; 4. severe mental disorders and dementia; 5. ALT or AST> 2.0 × ULN or previous known liver disease, such as acute hepatitis, chronic active hepatitis, cirrhosis; creatinine clearance <30ml/min or previous known severe kidney disease; 6. malignancy or positive for anti- cancer therapy; 7. with severe systemic disease, expected survival < 90 days; 8. pregnancy, lactation and pregnancy in patients plan; 9. seizures associated with patient; 10. researchers considered unsuitable to participate in the clinical patients studied.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood;Blood chemistry;Urine;Coagulation;EC; | — |
Countries
China
Contacts
Public ContactHe Mingli
Lianyungang City First People's Hospital
Outcome results
None listed