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The effect of dexmedetomidine on arterial baroreflex function during perioperative in hypertensive

The effect of dexmedetomidine on arterial baroreflex function

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004798
Enrollment
Unknown
Registered
2014-06-14
Start date
2014-07-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

arterial baroreflex function

Interventions

Dexmedetomidine group:Dexmedetomidine 0.5µg/kg
Control:Placebo

Sponsors

Anhui Province Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) patients undergoing general anesthesia for elective surgery, ASA I-II; (2) hypertensive patients, hypertension 1-2 grade; (3) aged 30-70 years old, male or female.

Exclusion criteria

Exclusion criteria: (1) severe kidney disease, severe cardiovascular and cerebrovascular diseases; (2) with contraindications of dexmedetomidine , such as sinus bradycardia, atrioventricular block; (3) history of substance abuse;

Design outcomes

Primary

MeasureTime frame
Baroreflex sensitivity;—

Contacts

Public ContactLi Juan

Anhui Province Hospital

huamuzi1999@126.com+86 13956005465

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026