Effect of dexmedetomidine postconditioning on renal protection in patients undergoing laparoscopic partial nephrectomy:a

Effect of dexmedetomidine postconditioning on renal protection in patients undergoing ischemia-reperfusion

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-14004766

Enrollment

Unknown

Registered

2014-06-06

Start date

2014-06-06

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal ischemia-reperfusion injury

Interventions

control group:Injection of 0.9% saline

DEX group:Injection of 0.6ug/kg dexmedetomidine postconditioning

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: According to TNM, choose the patients of preoperative diagnosis of tumor maximum diameter 4-6cm,without distant metastasis; ASA I-II, aged 18-65 years old; No previous history of cardiovascular disease, endocrine disease, acute renal disease, a history of renal transplantation, serum creatinine<1.5mg/dl, BUN<20mg/dl.

Exclusion criteria

Exclusion criteria: A history of cardiovascular disease, endocrine disease, acute renal disease, a history of renal transplantation, serum creatinine>1.5mg/dl, BUN>20mg/dl; The patients with significant inflammation (image data, blood, body temperature, etc.)

Design outcomes

Primary

Measure	Time frame
GRF;retinol-binding protein;Cystatin C;NGAL;	—

Countries

China

Contacts

Public ContactZhangYe

Second Affiliated Hospital of Anhui Medical University

zhangye_hassan@sina.com+86 13966768081

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026