Recurrent urinary tract infections
Conditions
Interventions
West-medicine Group:Levofloxacin (0.1 g QN, po) 4weeks + Furadantin (100mg, QN, po) 4 weeks + SMZ-CO (1pill, QN, po) 4 weeks
Or Cefuroxime (0.25g, QN, po) 4weeks if SMZ allergy
Very low doses of traditional Chinese medicine (TCM group based prescription 1/10 doses), 12weeks
TCM Group:Or ZiShen QingLi Decoction for 12 weeks if patients are deficient of Yin of Kidney
Sponsors
Yueyang Hospital of Integrated Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Comply with the western medical diagnostic criteria of chronic urinary tract infection (recurrent urinary tract infection); 2. Comply with the TCM diagnostic criteria of urinary tract infection; 3. Aged 18-75 years; 4. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. acute pyelonephritis or acute urinary tract infection occurred for the first time; 2. Deformity, stone or hydrops of urethra, detected by radiological examinations; 3. Urethral syndrome; 4. Chronic renal failure, serum creatinine=442 umol/L; 5. Pregnant or lactating (women at child-bearing period are requested to have urinary HCG test to detect pregnancy); 6. Allergic to the test drugs or ingredients of the TCM granules; 7. Severe damage of heart, liver or kidney, and other severe diseases including diabetes; 8. Severe central nervous system diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine WBC;Urine bacterial culture;Quality of Life Survey: The SF-36 scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| SIgA levels in urine;ß2-MG level in urine;NAG in Urine;RBP in urin; | — |
Countries
China
Contacts
Public ContactWang Yi
Yueyang Hospital of Integrated Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed