knee osteoarthritis
Conditions
Interventions
Jingui external lotion group:fumigating and washing with Jingui external lotion
Simulative external lotion group:Simulative placebo external lotion
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for knee osteoarthritis aged 50 to 80 years; (2) the Kellgren-Lawrence grading system shown Grade 3 or 4narrowing in medial joint space,received conservative treatment; (3) without serious medical history, without any severe vascular lesions on lower limbs; (4) without any study drug allergy, including contrast agent, no MRI contraindications; (5) volunteered for the researchers.
Exclusion criteria
Exclusion criteria: (1) have MRI contraindications,study drug allergy; (2) none degenerative osteoarthritis, such as rheumatoid arthritis, gouty arthritis, infectious arthritis, charcot arthritis, etc; (3) can't stop using painkillers; (4) fail to complete the course of treatment; (5) failed to obtain informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| American knee society knee score;tender point Visual Analogue Scale;enhanced rate in subchondral interesting regions;maximum upslope in subchondral interesting regions;enhancement rate of anterior and posterior periarticu synovial membrane; | — |
Contacts
Public ContactDa Guo
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed