Normal procalcitonin guides antibiotic therapy for acute exacerbation of chronic obstructive pulmonary disease-single center, prospective randomized control study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-14004726

Enrollment

Unknown

Registered

2014-05-28

Start date

2014-05-20

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute exacerbation of Chronic obstructive pulmonary disease

Interventions

antibiotic group:piperacillin/sulbatam

antibiotic group:antibiotic routine

Eligibility

Sex/Gender

All

Age

40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients admitted for AECOPD, aged elder than 40 years; 2. PCT level<0.1ng/ml 1 hour within admission..

Exclusion criteria

Exclusion criteria: 1. Intubation; 2. Fever (T=38?); 3. PCT level = 0.1 ng/ml 1 hour within admission; 4. no written informed consents; 5. Concurrent with pneumonia and/or chronic renal dysfunction; 6. Immunosuppressive therapy.

Design outcomes

Primary

Measure	Time frame
symptom scores after three days admission;The length of hospital stay;	—

Secondary

Measure	Time frame
Length of stay in ICU;ratio of re-admission within 30 days after discharge;	—

Countries

China

Contacts

Public ContactBIN CAO

Luhe hospital of Tongzhou district, Beijing, China

caobin1999@gmail.com+86 010-85231167

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 13, 2026