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A randomized controlled trial for comparing safety and efficacy of different doses thromblytic drugs catheter-directed thrombolysis in the treatment of deep venous thrombosis

A randomized controlled trial for comparing safety and efficacy of different doses thromblytic drugs catheter-directed thrombolysis in the treatment of deep venous thrombosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004715
Enrollment
Unknown
Registered
2014-05-25
Start date
2014-07-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

deep venous thrombosis

Interventions

Three groups(A, B, C):Urokinase 250,000 U

Sponsors

Nanjing Hospital Affiliated to Nanjing Medical University(Nanjing First Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients identified as acute deep vein thrombosis (Time of lower extremity symptoms occur time = 14 days, the imaging studies showed filling defects in deep venous lumen).

Exclusion criteria

Exclusion criteria: Past history of ipsilateral limb DVT; inferior vena cava thrombosis; cerebral vascular accident or neurosurgery after three months; active gastrointestinal bleeding; pregnancy and lactation; uncontrolled hypertension (> 180/100 mmHg); clotting disease and bleeding tendency; liver failure; bacterial endocarditis; diabetic retinitis

Design outcomes

Primary

MeasureTime frame
Thrombous chearance Rate;

Secondary

MeasureTime frame
Incidence of bleeding;Limb swelling disappearance rate;

Countries

China

Contacts

Public ContactGu Jian-ping
cjr.gujianping@vip.163.com+86 13505171786

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026