Skip to content

A randomized controlled study of Transcatheter arterial chemoembolization combined with autologous DC-CIK cells in the treatment of advanced hepatocellular carcinoma

A randomized controlled study of Transcatheter arterial chemoembolization combined with autologous DC-CIK cells in the treatment of advanced hepatocellular carcinoma

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004712
Enrollment
Unknown
Registered
2014-05-19
Start date
2012-09-10
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatocellular carcinoma

Interventions

Experimental group and control group:DC-CIK

Sponsors

Eastern Hepatobiliary Surgery Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
27 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosis of hepatocellular carcinoma by imaging and AFP; 2. Initial diagnosis and treatment, the patient is unable for surgical treatment; Had not received previous sorafenib, microwave, radio frequency, radiation and any other systemic therapy; 3. BCLC C; 4. Normal organ function; 5. Expected survival = 12 weeks; 6. For this study has been fully understood and voluntarily signed informed consent; 7. approved by the hospital ethics committee.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Known for contrast agents, chemotherapy drugs, interleukin-drug allergy or allergy to all biological agents; 3. Severe liver function impairment, Child-Pugh grade C and above in phases; 4. Suffering from any other malignancy within five years; 5. There uncontrolled active infection clinically; 6. With severe systemic disease, systemic failure by the situation; 7. Also accept other systemic anti-cancer therapy (radiotherapy of bone metastases is not restricted); 8. Estimates of the lack of compliance of patients to participate in clinical research.

Design outcomes

Primary

MeasureTime frame
OS;

Secondary

MeasureTime frame
Lymphocyte subsets;PFS;

Contacts

Public ContactQu Zengqiang

Eastern Hepatobiliary Surgery Hospital

ZQQu@163.com+86 13801959517

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026