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Effects of Penehyclidine hydrochloride on the propofol dose requirement and Bispectral Index for loss of consciousness

Effects of Penehyclidine hydrochloride on the propofol dose requirement and Bispectral Index for loss of consciousness

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004692
Enrollment
Unknown
Registered
2014-05-24
Start date
2014-06-02
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

general anesthesia patients for select surgery

Interventions

Group PH:v.i. penehyclidine hydrochloride 0.012 mg/kg
Control:v.i. penehyclidine hydrochloride 0.012 mg/kg
Control :NS 10ml

Sponsors

Department of Anesthesiology,West China Hospital,Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASA physical status I or II, aged 18-65 yr, undergoing elective surgery with general anesthesia

Exclusion criteria

Exclusion criteria: Exclusion criteria included obesity (Body Mass Index >28 kg/m2), pregnancy, closed-angle glaucoma,suspected or known difficult airway, patients with contraindication to propofol, with cardiovascular and neurological diseases, impairment of renal, hepatic function, hearing impairment, substance abuse and those taking drugs affecting the consciousness.

Design outcomes

Primary

MeasureTime frame
OAA/S score;predicted effect site concertration C;—

Countries

China

Contacts

Public ContactLiang Peng
liangpeng_world@foxmail.com+86 18980602201

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026