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Anticoagulation for the treatment of portal vein thrombosis in liver cirrhosis: An open-label, prospective, multi-center, randomized controlled trial

Anticoagulation for the treatment of portal vein thrombosis in liver cirrhosis: An open-label, prospective, multi-center, randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004690
Enrollment
Unknown
Registered
2014-05-22
Start date
2014-07-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver cirrhosis

Interventions

Anticoagulation/no anticoagulation group:Anticoagulation

Sponsors

Department of Gastroenterology, General Hospital of Shenyang Military Region
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Informed consent is provided;2. Age ranges from 18 to 75 years old;3. Liver cirrhosis is definitely diagnosed by the clinical presentations and images or liver biopsy if necessary;4. Portal vein thrombosis is definitely diagnosed by image;5. Child-Pugh score is less than 13 points;6. No active bleeding.

Exclusion criteria

Exclusion criteria: 1. Do not meet the inclusion criteria; 2. Pregnancy or breast-feeding; 3. Malignancy (e.g. hepatocellular carcinoma); 4. HIV infection and AIDS-related diseases or other severe diseases; 5. Severe cardiac or respiratory diseases;

Design outcomes

Primary

MeasureTime frame
Portal vein recanalization rat;

Secondary

MeasureTime frame
Incidence of upper gastrointestinal bleeding;Incidence of variceal bleeding;Incidence of hepatic decompensation;Overall survival;Incidence of anticoagulation-related complication;

Countries

China

Contacts

Public ContactXiaozhong Guo
guoxiaozhong1962@163.com+86 024 28897603

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026