pain
Conditions
Interventions
1:Strategy for postoperation analgesia
2:morphine1mg/ml+0.9%NS to 100ml for 48h
3:Strategy for postoperation analgesia:intravenous patient control analgesia(PCA)
concentation:morphine1mg/ml+dezocine 0.05mg/ml+0.9%NS to 100ml for 48h
bolus:1ml
lock time:8 min
4:Strategy for postoperation analgesia:intravenous patient control analgesia(PCA)
concentation:morphine1mg/ml+dezocine 0.1mg/ml+0.9%NS to 100ml for 48h
Sponsors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Male and female aged 18 to 65 years old; 2.Able and willing to provide signed informed consent; 3. Schedule for thoracotomy; 4. American Society of Anesthesiologist physical status?~?; 5.Apply for postoperative analgesia.
Exclusion criteria
Exclusion criteria: patients are excluded from our study when: 1) their Body Mass Index are less than 19 or greater than 31; 2) they have a history of chronic pain; 3)they have a history of drug or alcohol abuse; 4)they take analgesic or opioids 12 h before surgery; 5) they have status of contraindications to the drugs we use in our study; 6) immediate extubation is not planned after surgery; 7) they cannot understand and make use of the PCA device; 8) there is existence of pregnancy, lactation, liver and kidney failure or respiratory failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Morphine consumption at 1/6/24/48 hours postoperat;visual analogue scale at 1/6/24/48 hours postopera;PONV;postoperative pruritus;postoperative dizziness;postoperative sedatio;age;gender;Body Mass Index;ASA classification of patients; | — |
Secondary
| Measure | Time frame |
|---|---|
| operation duration;intraoperative sulfentanil consumption;expired sevoflurane concentration at different tim; | — |
Countries
China
Contacts
Public ContactSun Li
Outcome results
None listed