non-alcoholic fatty liver disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? no alcohol consumption or alcohol dose <70 g/wk for women and <140 g/wk for men; ?With the exception of viral hepatitis, drug-induced liver disease, total parenteral nutrition, and other diseases can lead to fatty liver disease; ?Liver imaging findings the diagnosis of diffuse fatty liver and no other reason can explain; ?Patients with unexplained and persistent increase in serum ALT and (or), AST, GGT of at least 1.5 times the limit of normal; ?body mass Index (BMI) between 25 and 40Kg/?; ?18-65 years of age; ?Signed informed consent and agreed to enter the study.
Exclusion criteria
Exclusion criteria: ?alcohol consumption and alcohol dose >70 g/wk for women and >140 g/wk for men; ?Without the exception of viral hepatitis, drug-induced liver disease, total parenteral nutrition,and other diseases can lead to fatty liver disease; ?patient receiving hepatotoxicand insulin-sensitizing medication; ?Over the past year had bariatricsurgery; ?used weight loss medication or program in the previous 3 months; ?Patients with pregnancy and lactation; ?patients with mental disorder can't cooperate, don't sign the informed consent; ? age 65 years; ?patients with pacemaker or metallic implants and with claustrophobia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visceral fat content;liver fa; | — |
Secondary
| Measure | Time frame |
|---|---|
| weight;waist circumference;abdominal circumference;liver enzyme;serum lipi; | — |
Countries
China