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The effect of epidural dexmedetomidine on the intestinal peristalsis function after colorectal operation

The effect of epidural dexmedetomidine on the intestinal peristalsis function after colorectal operation

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004644
Enrollment
Unknown
Registered
2014-05-14
Start date
2014-05-14
Completion date
Unknown
Last updated
2021-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal diseases

Interventions

Levobupivacaine group:none
Morphine group:add some dose of morphine to levobupivacaine
Dexmedetomidine group:add some dose of morphine to levobupivacaine

Sponsors

Second affiliated Hospital, Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiology Physical Status I/II patients undergoing colorectal operation and agreed to sign the informed consent of patients.

Exclusion criteria

Exclusion criteria: None of the subjects included had neurologic or psychiatric disease, known allergy to local anaesthetic, a history of gastrointestinal motility disorders, renal or hepatic insufficiency, bleeding or coagulation test abnormalities, or were receiving anticoagulant.

Design outcomes

Primary

MeasureTime frame
postoperative pain score;The postoperative first flatus time;The postoperative first feces time;The total dose of postoperative analgesic;The time to the first postoperative analgesi;

Secondary

MeasureTime frame
Side-effects related to dexmedetomidine and morphi;vital signs during the first 6 hours after operati;

Countries

China

Contacts

Public ContactCui Xiao-Guang
cuixiaoguang@hotmail.com+86 13796022830

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 2, 2026