Primary dysmenorrhea
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged from 18 to 30 years old without any history of delivery;2. Menstrual cycle was 28 ± 7 days during last 3 months;3. The diagnostic criteria of primary dysmenorrhea in the Primary Dysmenorrhea Consensus Guideline[20];4. Complied with the syndrome of stagnation of qi and blood or the syndrome of obstruction due to cold-dampness;5. Menstrual pain scored more than 40 mm on a 100 mm Visual Analogue Scale (VAS);6. Keep a dysmenorrhea diary during the baseline menstrual period;7. Agree to sign informed consent form.
Exclusion criteria
Exclusion criteria: 1. With secondary dysmenorrheal caused by endometriosis, uterine myoma, endometrial polyps, pelvic inflammatory disease, and other gynecological problems; 2. With Serious comorbid conditions (for example, life-threatening condition or progressive central disorder); 3. Any other condition likely in the judgment of the investigator that make the patient unable to complete, or is unsuitable for the study; 4. with uncontrolled diagnosed psychiatric disorders; 5. A woman who is planning to have a baby; 6. Taking anti-depressant, anti-serotonin, barbiturate, or psychotropic drugs in past 2 weeks; 7. Receiving or received any other treatment of primary dysmenorrhea in past 3 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PGE2/PGF2; | — |
Countries
China