Hypotension
Conditions
Interventions
Two groups:Administration Norepinephrine by intravenous infusion versus administration by intravenous bolus Approx 30 min, continuous infusion or Q1min bolus
Sponsors
The Chinese University of Hong Kong
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologists Physical Status 1 or 2 non-labouring normotensive parturients with term singleton pregnancies who are scheduled for elective or semi-elective Caesarean section and who have been judged suitable and have agreed to have spinal anaesthesia according to usual clinical criteria. Patients will only be eligible for inclusion if their mean baseline systolic blood pressure (SBP) is within the range 90–140 mmHg.
Exclusion criteria
Exclusion criteria: Patients with known fetal abnormality, pre-existing or pregnancy-induced hypertension, known cardiovascular or cerebrovascular disease, thrombocytopaenia, coagulopathy, or any medical contraindication to spinal anaesthesia, weight 100 kg, height 180 cm, inability or refusal to give informed consent, age < 18 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Median absolute performance error (MDAPE)of systolic blood pressure control; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in heart rate and cardiac output, incidence of maternal nausea and vomiting; | — |
Countries
Chiina
Contacts
Public ContactProfessor Warwick D. Ngan Kee
The Chinese University of Hong Kong
Outcome results
None listed