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Comparison live birth rate in hormone replacement frozen embryo transfer cycles with vaginal gel and intramuscular progesterone: A prospective randomized trial in Chinese population

DNA methylation studies during the implantation window in human endometrium

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004565
Enrollment
Unknown
Registered
2014-02-06
Start date
2010-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

A:vaginal progesterone gel
B:intramuscular progesterone

Sponsors

Renji Hospital, Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. September 1, 2010 to January 31, 2013; 2. Hormone replacement FET cycles; 3. Women aged 20 to 35 years old; 4. D3 frozen embryos available; 5. Endometrium thickness =7mm on endometrial transformation day; 6. Women who are capable of giving informed consent.

Exclusion criteria

Exclusion criteria: 1. Women with diagnosed uterus abnormality: malformed uterus (uterus unicornis, septate uterus, duplex uterus, u terus bicomis), adenomyosis, submucous myoma, intrauterine adhesion; 2. Women who have experienced recurrent spontaneous abortion (including biochemical pregnancy abortion) more than 2 times; 3. Embryo transferred failure more than 2 times(including biochemical pregnancy abortion); 4. Women with medical condition that represent contraindication to assisted reproductive technology and/or pregnancy; 5. Women who are taking any medication impacting reproductive or metabolic function that should not be discontinued, such as anti-diabetic agents, certain anti-hypertension agents that known to affect reproductive function or metabolism (diazoxide, ACE inhibitors, calcium channel blockers), herbal supplement, acupuncture; 6. Endometrium thickness <7mm on endometrial transformation day; 7. Women who are unable to comply with the study procedures.

Design outcomes

Primary

MeasureTime frame
Live birth rate;

Secondary

MeasureTime frame
Clinical pregnancy rate;Abortion rate;Implantation rate;Ectopic pregnancy rate;

Countries

China

Contacts

Public ContactYun Sun

Renji Hospital, Shanghai Jiaotong University School of Medicine

syun163@163.com+86 13601634278

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 4, 2026