dental ulcer, gingivitis or dry eye
Conditions
Interventions
Treatment Group: dental ulcer with yin deficiency:bland diet and zhibai dihuang pills
Control group: dental ulcer with yin deficiency:bland diet
Treatment Group: gingivitis with yin deficiency:bland diet and zhibai dihuang pills
Control group: gingivitis with yin deficiency:gbland diet
Treatment Group: dental ulcer with excess heat:Huanglianjiedu Decoction
Control group: dental ulcer with excess heat:placebo
Treatment Group: gingivitis with excess heat:Huanglianjiedu Decoction
Control group: gingivitis with excess heat:placebo
reatment Group: Oral herpes simplex with excess h:Huanglianjiedu Decoction
Control group:Oral herpes simplex with excess heat:placebo
Sponsors
Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. "Shanghuo"(dental ulcer, gingivitis or dry eye) patients of yin deficiency; 2. "Shanghuo"(dental ulcer, gingivitis or dry eye) patients of excessive heat; 3. Patients of yin deficiency prone to "Shanghuo"(dental ulcer, gingivitis or dry eye episodes of >= 15 times per year); 4. Patients of damp-heat prone to "Shanghuo"(dental ulcer, gingivitis or dry eye episodes of >= 15 times per year); 5. Moderate physical quality population (as normal control); 6. Aged between 18 to 60 years; 7. Volunteered to participate in this study and agreed to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients suffering from mental illness, cancer and other serious diseases; 2. Pregnant or lactating women; 3. Can't tolerate the durgs of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood routine;Urine routine;liver function;Serum metabolomics;serological proteome analysis;Oral microbial community structure; | — |
Countries
China
Contacts
Public ContactFan Yong-sheng
Zhejiang Chinese Medical University
Outcome results
None listed