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A Randomized controlled trial study on the prognosis of hepatectomy for hepatocellular carcinoma with vs without hepatic blood inflow occlusion

A Randomized controlled trial study on the prognosis of hepatectomy for hepatocellular carcinoma with vs without hepatic blood inflow occlusion

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004531
Enrollment
Unknown
Registered
2014-04-18
Start date
2014-04-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatocellular carcinoma

Interventions

hepatic blood inflow occlusion:hepatic blood inflow occlusion
control:the hepatic blood inflow without occlusion

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 100 Years

Inclusion criteria

Inclusion criteria: (1) Patients generally good, no heart, lung, kidney, brain and other diseases; (2) liver function is normal or only mild damage, according to liver function (Child-Pugh classification of liver function) of Class A; or liver function returned to Class A from B grade after short-term treatment; (3) liver reserve function (eg ICGR15) basically within the normal range; (4) single liver, smooth surface, surrounded by boundaries or false capsule formation, liver tissue damaged by tumor 30 %, normal liver side compensatory increases significantly, reaching more than 50% of the whole liver tissue; (5) multiple tumors, tumor nodules less than 3, limited in one segment or one lobe; (6) hepatic vein, portal vein, inferior vena cava, and bile duct were not invaded by tumor; (7) No adjacent organs invasion, without hilar lymph node or distant metastasis; (8) tumor can be completely resected by segment, lobe or semi-resection according to liver anatomical boundaries; (9) liver resection margin from the tumor boundary = 1cm; if the cutting edge of <1cm, the edge of the remnant liver histology shows no residual tumor cells.

Exclusion criteria

Exclusion criteria: (1) unwilling or unsuitable for liver resection; (2) patients suffering from other malignancies simultaneously; (3) hepatitis B, hepatitis C patients in active state; (4) coagulopathy; (5) extrahepatic metastasis.

Design outcomes

Primary

MeasureTime frame
post-operative survival;recurrence rate;tumor free rate;complication rate;

Countries

China

Contacts

Public ContactZeng Yong

West China Hospital, Sichuan University

zengyong@medmail.com.cn+86 18980601472

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026