diminished ovarian reserve
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Owing to the lack of a standard definition of ovarian reserve, the decrease of ovarian reserve in patients was assumed based on previous reports 15-18 if they satisfied at least one of the following conditions: 1. AFC in bilateral ovarian =5; 2. basal follicle stimulating hormone (FSH) levels =10 IU/L or follicle stimulating hormone/luteinizing hormone (FSH/LH) ratio =3.6 detected at least twice, or age =35 years old; and 3. a history of pelvic surgery.
Exclusion criteria
Exclusion criteria: Patients with endometriosis, immune infertility, and intracytoplasmic sperm injection for male factor infertility were excluded from this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AFC;basal estrogen level;basal FSH level;FSHR protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| basal luteinizing hormone (LH) level;FSH/LH ratio;AMH level;ovarian artery resistance index (RI);ovarian artery pulsatility index (PI);systolic/diastolic flow velocity ratio (S/D; | — |
Countries
China
Contacts
The second hospital affiliated to Shandong University of traditional Chinese medicine