Stable Angina
Conditions
Interventions
Experimental:Revised "Shensu Huxin" decoction
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18-70 years; (2) Angina classification II-III; (3) Can be relieved quickly after nitrate esters while angina pectoris attacks; (4) Be able to complete the exercise test and with positive result; (5) Informed consent.
Exclusion criteria
Exclusion criteria: (1) Myocardial infarction, unstable angina pectoris, or Coronary artery revascularization (surgical bypass operation or angioplasty) history in 3 months; (2) With other heart diseases, neurosis, climacteric syndrome, hyperthyrea, cervical spondylosis, Gallbladder cardiac syndrome, Gastro esophageal reflux disease, or hiatal hernia which can also cause chest pain; (3) Abnormal appearance of resting electrocardiogram as follows: complete left bundle branch block, pre-excitation syndrome, Ventricular pacing rhythm, ST segment depression more chan 0.1mv, or left ventricular hypertrophy; (4) With uncomtrolled symptomatic heart failure or left ventricular ejection fraction =40% on cardiogram; (5) With ralative or absolute contraindication of exercise load test: Left main coronary artery stenosis, in severe stenosis valvular heart disease, electrolyte abnormalities, severe hypertension, hypertrophic cardiomyopathy or other types of outflow obstruction; (6) With tachyar rhythmia or slow arrhythmia which requests treatments; (7) Active liver disease, or with agnogenic persistent rising of serum transaminase, or ALT?AST>2 times of the high limits of the normal reference value; (8) Abnormal renal function (serum creatinine > high limit of the normal reference value); (9) In combination of severe primary disease of respiratory apparatus, hematopoietic system, or malignant tumor; (10) Pregnant women, lactating women, or women of childbearing age with fertility requirements; (11) Patients with mental disorders or cognitive dysfunction; (12) Patients who are with bad compliance, not able to be interviewed regularly, or not able to fill the Patients' Diary Card according to the doctors' requirements; (13) Attended other clinical trials or already accepted the random group dividing in this trial; (14) Other situations that the researchers consider not fit for this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treadmill test standard;Angina episodes;ECG standard;Echocardiography;Standards of TCM symptoms;Safety Evaluation;Adverse event; | — |
Countries
China
Contacts
Public ContactHuanlin Wu
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed