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A randomized controlled trial of protocol-directed versus physician-directed weaning in neurocritical care patients

A randomized controlled trial of protocol-directed versus physician-directed weaning in neurocritical care patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004458
Enrollment
Unknown
Registered
2014-01-23
Start date
2011-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurocritical Care

Interventions

protocol-directed group:protocol-directed weaning
physician-directed group:physician-directed weaning

Sponsors

Xuanwu Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. aged between 18 to 80 years old; 2. mechanical ventilation for more than 24 hours.

Exclusion criteria

Exclusion criteria: 1. irreversible respiratory failure caused by neurodegenerative disorders, such as amyotrophic lateral sclerosis, spinal muscular atrophy,progressive bulbar palsy, primary lateral sclerosis,Alzheimer's disease,multiple system atrophy; 2. endotracheal intubation for more than 2 weeks but refused to tracheotomy; 3. withdraw from treatment; 4. end-stage of illness; 5. Pregnancy.

Design outcomes

Primary

MeasureTime frame
weaning time;duration of mechanical ventilation;—

Secondary

MeasureTime frame
weaning success rate;ventilator-associated pneumonia incidence;ICU mortality;length of ICU stay;ICU cost;—

Countries

China

Contacts

Public ContactSu Yingying

Xuanwu Hospital, Capital Medical University

tangsuyingying@sina.com+86 15901361953

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026