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The efficacy and mechanism of Repetitive transcranial magnetic stimulation in negative symptoms of schizophrenia and auditory hallucination

The efficacy and mechanism of Repetitive transcranial magnetic stimulation in negative symptoms of schizophrenia and auditory hallucinatio

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004451
Enrollment
Unknown
Registered
2014-02-04
Start date
2014-02-15
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenic

Interventions

Sponsors

First Affiliated Hospital, College of Medicine, Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. signed a written informed consent, and willing to participate in testing and treatment; 2. Aged 18 to 60 years old; 3. in accordance with the DSM - IV schizophrenia diagnosis standard; 4. voices symptom scores of 4 or more points in PANSS score or scoring 19 points or more negative symptoms and auditory hallucination score < 4 points; 5. in the treatment of patients with fixed dose of antipsychotic drugs 2 or more than two months, hearing voices or negative symptoms without further improvement; 6. right-handed.

Exclusion criteria

Exclusion criteria: 1. excluded patients with epilepsy, body inside the metal and acute cerebrovascular accident patients; 2. excluded patients with severe nerve, heart, liver, kidney, endocrine, blood system and so on disease or may interfere with the test evaluation body's disease patients; 3. excluded patients with organic mental disorders and mental retardation; 4. out of alcohol and drug dependence; 5. accept no convulsions within three months of electroconvulsive therapy; 6. pregnant women and nursing mothers.

Design outcomes

Primary

MeasureTime frame
the score of PANS;

Secondary

MeasureTime frame
cognitive function;

Countries

China

Contacts

Public ContactHuang Manli

First Affiliated Hospital, College of Medicine, Zhejiang University

hml1208@sina.com+6 13957162975

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026