Depression
Conditions
Interventions
two:Neuropsychological assessmen
one:active rTMS combined with prozac
three:sham rTMS combined with prozac
Sponsors
First Affiliated Hospital, College of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
13 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1. patients with a DSM-IV clinical criteria for major depressive episode; 2. patients who are experiencing their first depressive episode; 3. patients aged between 13-17 years old, males and females; 4. right-handed; 5. Naked eyes or corrected to normal vision.
Exclusion criteria
Exclusion criteria: 1) had a history of serious physical, cerebral organic history or head injury; 2) mental retardation; 3) brain structural abnormalities; 4) uncooperative or can not effectively accomplish this experimenter; 5) drugs, alcohol or other psychotropic active substance abusers; 6) with cardiac pacemakers, insulin pumps, artificial heart valves and other metal in body.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognitive function;the score of MADRS;Modified score of child depression rating scale;fractional anisotropy (FA) valus;ampli-tude of low frequency fluctuation, ALF; | — |
Countries
China
Contacts
Public ContactHuang Manli
First Affiliated Hospital, College of Medicine, Zhejiang University
Outcome results
None listed