FindTrial
Sign In

Increased growth factors play a role in wound healing promoted by noninvasive oxygen-ozone therapy in diabetic patients with foot ulcers

Increased growth factors in wounds of diabetic foot ulcer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004415
Enrollment
Unknown
Registered
2014-03-20
Start date
2014-03-31
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic foot ulcer

Interventions

general group:traditional treatment
experimental:traditional treatment+individualized therapy

Sponsors

Nanfang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Hospitalized patients with type 2 diabetes mellitus (T2DM) from the Department of Endocrinology & Metabolism, Nanfang Hospital, Southern Medical University; 2. Aged 18 years and older; 3. DFU of Wagner classification stage 2, 3 or 4 for 1 week or longer; 4. ABI>0.7.

Exclusion criteria

Exclusion criteria: (1) gangrenous foot ulcers; (2) active osteomyelitis; (3) a history of collagen diseases; (4) hyperthyroidism; (5) pregnancy or nursing; (6) hemoglobin A1c (HbA1c) levels > 10.5%; (7) ankle brachial index (ABI) 133 umol/L or dialysis, and (11) a known allergy to ozone.

Design outcomes

Primary

MeasureTime frame
effective rate;—

Countries

China

Contacts

Public ContactYaoming Xue

Dept. Endocrinology & Metabolism, Southern Medical University, Guangzhou, China

xymbright@163.com+86 020 61641631

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 8, 2026