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The Effects of norepinephrine on cerebral oxygen metabolism in elderly surgery patients with fluid restriction

The Effects of norepinephrine on cerebral oxygen metabolism in elderly surgery patients with fluid restriction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004329
Enrollment
Unknown
Registered
2014-02-07
Start date
2014-02-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cognitive dysfunction

Interventions

conventional group:Fluid therapy
fluid restriction group:Small dose norepinephrine

Sponsors

Zhongda Hospital,Southeast University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 75 Years

Inclusion criteria

Inclusion criteria: 40 ASA grade I, II elderly patients, aged 60-75 years, undergoing elective operation

Exclusion criteria

Exclusion criteria: Patients who have severe cardiac diseases (cardiac function classification at III-IV or myocardial infarction within 3 months), severe infection, hematonosis, severe liver or kidney dysfunction(serum creatinine 50% higher than normal value), and patients whose MAP over 90mmHg or blood lose over 1000ml would be excluded.

Design outcomes

Primary

MeasureTime frame
Cerebral oxygen uptake rate (CERO2);Carotid artery lactate concentration difference;cognitive function tests (MMS);—

Countries

China

Contacts

Public ContactQiu Xiaodong
qxdong@hotmail.com+86 13815880193

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026