degenerative articular cartilage defects of the knee joint
Conditions
Interventions
Microfracture& Injection of Stem Cells:Arthroscopic microfracture and injection of autologous mesenchymal stem cells
Control:arthroscopic debridement alone
Sponsors
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: A clinical diagnosis of degenerative osteoarthritis, symptomatic osteoarthritis accompanied by cartilage defects
Exclusion criteria
Exclusion criteria: Age>70, Knee flexion deformity, injury of ligament instability,knee varus malalignment (>10 degrees), Systemic bone arthritis,Multiple injuries, patellar and tibial lesion, accept the stable ligament operation and follow-up less than 24 mon,non articular cartilage injury in the weight bearing area under arthroscopy,Not willing to participate in this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The HSS knee score;The Tegner knee score; | — |
Secondary
| Measure | Time frame |
|---|---|
| the level of pain; | — |
Countries
China
Contacts
Public ContactYan Xiong
Dept.of Joint and Orthopedic Surgery, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Outcome results
None listed