The role of inhibition of return ability of orbitofronal cortex in anti-depressant treatment

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-14004309

Enrollment

Unknown

Registered

2014-02-22

Start date

2014-03-16

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

Experimental group of attentional training:Attentional training

Control group of attentional training:Sham attentional training

Routine antedepressant group (SSRI):Routine anti-depressan

TMS treatment group target at PFC:TMS treatment target at PFC

TMS treatment group target at OFC:TMS treatment target at OFC

Sham TMS group:Sham TMS treatment

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Scoring 20 or higher on HDRS and diagnosis of MDD by a psychiatrist according to the DSM-IV criteria

Exclusion criteria

Exclusion criteria: Severe head trauma and learning disabilities, current or lifetime psychotic symptoms, bipolar disorder, and alcohol or substance abuse within the past 6 months.

Design outcomes

Primary

Measure	Time frame
Cerebral neurotransmitter level;cerebral activation level;depression severity;Inhibition of return ability;	—

Countries

China

Contacts

Public ContactDai Qin

The Nursing department, the Third Military Medical University

daiqin101@hotmail.com+86 13452113607

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026