Psoriasis
Conditions
Interventions
Ammonia peptide hormones:Ammonia peptide hormones
Treatment Group:Oxymatrine
Contrast Group:Acitretin Capsules
Compound glycyrrhizin glucoside Group:Compound glycyrrhizin glucoside
Oxymatrine + compound glycyrrhizin glucoside:Oxymatrine + compound glycyrrhizin glucoside
Oxymatrine + compound glycyrrhizin glucoside:Oxymatrine + compound glycyrrhizin glucoside + black light
Black light:Black light
compound glycyrrhizin glucoside + black light:compound glycyrrhizin glucoside + black light
Sponsors
General Hospisal of Ningxia Medical University
Eligibility
Sex/Gender
All
Age
12 Years to 56 Years
Inclusion criteria
Inclusion criteria: Psoriasis patients, received systemic treatment at least once previously.
Exclusion criteria
Exclusion criteria: Patients who are allergic to oxymatrine, patients who are suffering from sever liver and kidney damage, mental illness, hematopoietic dysfunction and other serious organic disease, received immunosuppressor, high doses of glucocorticoid or retinoid in the past 4 weeks, pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Psoriasis area and severity index;Skin classification;Whole blood viscosity;T-AOC;MDA;SOD;GSH-Px;Immune globulin+ Complement;TNF-alpha;ICAM-1;IL-8;IL-10;Terminal deoxynucleotidyl transferase-mediated dUT;VEGF;MMP;ESAF;MCP-1; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dermatology life quality index;Pathological changes of skin;Routine blood tests;Routine biochemical examinations;Routine urine tests;Mitotic figure;PCNA;tumor suppressor gene-p53;The proliferation of tumor antigen-ki6; | — |
Countries
China
Contacts
Public ContactHuijuan Shi
General Hospisal of Ningxia Medical University
Outcome results
None listed