Does dexmedetomidine has cardiac protection effect for non-cardiac surgery: A randomised controlled trial.

Myocardial protective effect of demedetomidine during non-cardiac surgery in patients wi?coronary heart disease

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-14004266

Enrollment

Unknown

Registered

2014-02-13

Start date

2014-03-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary heart disease

Interventions

2:dexmedetomidine

1:NS

Eligibility

Sex/Gender

All

Age

41 Years to 75 Years

Inclusion criteria

Inclusion criteria: Confirmed by coronary angiography with coronary heart disease or have a typical angina pectoris, myocardial infarction and other clinical history and ecg changes. All patients with preoperative no electrolyte disorders and infection, immune disease, endocrine system, in the near term is not taking non-steroidal anti-inflammatory drugs and hormones

Exclusion criteria

Exclusion criteria: Patients with a history of hypertension, hypotension, diabetes mellitus, dysrhythmia, cerebrovascular disease, severe arrhythmia, heart failure, taking non-steroidal anti-inflammatory drugs and hormonal medications for underlying diseases, and any known sensitivity to study medications or previous anesthetic exposure within 1 year were excluded.

Design outcomes

Primary

Measure	Time frame
IL-6;	—

Countries

China

Contacts

Public ContactXu Lili

Department of Anesthesiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University

xulili1202@hotmail.com+86 13858115478

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026