Gastrointestinal Tumor
Conditions
Interventions
case group:DEX+Sufentanil
control group:Sufentanil
Sponsors
Beijing Union Medical College Hospital Anesthesiology
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. ASA grade I-III; 2. Aged 40-80 years old, male or female, BMI <30kg/m2; 3. no history of serious cardiovascular and respiratory diseases; 4. in patients with primary disease, preoperative examination to exclude distant metastasis-related, did not receive radiotherapy or chemotherapy; 5. patients have agreed to use the PCA analgesia.
Exclusion criteria
Exclusion criteria: 1. With severe central nerve system disease or surgery history; 2. there is a clear mental illness, recent use of antipsychotic drugs, alcohol or drug addiction history; 3. have sick sinus syndrome, severe sinus bradycardia (heart rate 177µmol / L; active liver disease); 5. hyperthyroidism or hypothyroidism, diabetes patients; 6. palliative surgery because of inable to remove the tumor or extensive intra-abdominal metastasis; 7. Serious adverse reactions of anesthesia during surgery (airway difficulties, allergic reactions) and postoperative intensive care unit if needed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD4;CD8;NK;Cortisol;AIS score;VAS score;Ramsay score;SDS score;SAS score;time of postoperative flatu; | — |
Secondary
| Measure | Time frame |
|---|---|
| alb;PA;CRP;Peripheral blood mononuclear cell; | — |
Countries
China
Contacts
Public ContactChen Feng
Beijing Union Medical College Hospital
Outcome results
None listed