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Combined Phacoemulsification-Endoscopic Cyclophotocoagulation versus Phacoemulsification alone in Primary Angle-Closure Glaucoma: A Randomized Controlled Trial

Combined Phacoemulsification-Endoscopic Cyclophotocoagulation versus Phacoemulsification alone in Primary Angle-Closure Glaucoma: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004233
Enrollment
Unknown
Registered
2014-02-04
Start date
2014-02-13
Completion date
Unknown
Last updated
2018-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

Experimental group:-Combined Phacoemulsification-Endoscopic Cyclophotocoagulation(Phaco-ECP) -Phacoemulsification, for two years
Control group:Phaco-ECP, Phacoemulsification to remove the cataratous lens and insertion of an intraocular lens and endoscopic cyclophotocoagulation to ablate the ciliary processes to reduce aqueous p

Sponsors

Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. A diagnosis of PACG; 2. Requiring 2 or more IOP-lowering drugs to control IOP, or IOP >21mmHg on maximally tolerable drugs; 3. Able and willing to give informed consent, prior to randomization; 4. Older than 18 years of age.

Exclusion criteria

Exclusion criteria: 1. Previous intraocular surgery or cyclophotocoagulation, with the exception of laser peripheral iridotomy and argon laser peripheral iridoplasty; 2. Secondary causes of angle closure including iridocorneal-endothelial syndrome, neovascular glaucoma etc.; 3. Unable to cooperate for reliable visual field and OCT examination.

Design outcomes

Primary

MeasureTime frame
The primary outcome measures are IOP and the number of IOP-lowering drugs.;

Secondary

MeasureTime frame
Secondary outcome measures include BCVA, surgical complications, and need for additional surgical interventions.;

Countries

China

Contacts

Public ContactProf. Tham Chee Yung Clement

Hong Kong Eye Hospital

clemtham@cuhk.edu.hk+86 39535823

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 3, 2026