Acute myocardial infarction
Conditions
Interventions
research group:Oral aspirin 300mg and clopidogrel + tirofiban + directly perform PCI inter-coronary artery
Control:Oral aspirin 300mg and clopidogrel + directly perform PCI inter-coronary artery
Sponsors
Tianjin Tifth Central Hospital
Eligibility
Sex/Gender
All
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. presence of angina for < 12 hours prior to hospital admission; 2. elevation of ST-segment in at least 2 consecutive ECG leads; and 3. elevation of serum cardiac troponin T or myocardial enzymes.
Exclusion criteria
Exclusion criteria: (1) manifestation of cardiac shock or a blood pressure (BP) 180 mmHg despite intravenous use of antihypertensives), major surgery or trauma within 6 weeks, hemorrhagic stroke within 6 months, major gastrointestinal bleeding within 6 months; (5) serum hemoglobin < 100 g/L or platelets < 100×10^9/L; (6) presence of severe renal or hepatic dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD62p;PAC-1;endothelial microparticles (EMPs);vascular cell adhesion molecule-1(VCAM-1).;intracellular adhesion molecule-1 (ICAM-1); | — |
Countries
China
Contacts
Public ContactKuan Wang
Tianjin Tifth Central Hospital
Outcome results
None listed