recurrent spontaneous abortion
Conditions
Interventions
Cyclosporin A:oral Cyclosporin A 50-75mg t.i.d.(q8h) ×20-30days
Dydrogesterone:oral Dydrogesterone 10mg t.i.d.(q8h) ×20-30days
Cyclosporin A+Dydrogesterone:oral Cyclosporin A 50-75mg and Dydrogesterone 10mg t.i.d.(q8h) ×20-30days
Sponsors
The Obstetrics & Gynecology Hospital, Fudan University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Women who had experienced at least two consecutive abortions with the same husband, and only those women for whom no explanation could be found in the following assessments for their recurrent abortions were includedpelvic ultrasonography, hysterosalpingography or hysteroscopy, blood tests (rhesus factor, complete blood count), thyroid function tests (T3, T4, thyroid stimulating hormone), immunological tests (antiphospholipid antibodies, lupus antibodies), TORCH: IgM, chromosomal analysis, mid luteal phase progesterone levels, serum prolactin levels, a high vaginal swab for bacteriology, and chromosomal and semen analyses in husbands.
Exclusion criteria
Exclusion criteria: Women with various tumors, liver and kidney dysfunction, blood diseases, severe systemic infection or decreased immunity are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ultrasound image;Liver function tests;Kidney function tests;Blood test;Urine test;CsA blood concentratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| ßHCG;P;Treg cell percentag; | — |
Countries
China
Contacts
Public ContactLi Da-jin
The Obstetrics & Gynecology Hospital of Fudan University
Outcome results
None listed