The metabolic mechanism of therapeutic hypothermia and the effects of innovative endpoint based on rest metabolic ratio on outcomes

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-14004212

Enrollment

Unknown

Registered

2014-01-24

Start date

2014-01-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic Brain Injury

Interventions

Reserch Group:Reduce Metabolic Rate

Control group:Reduce Metabolic Rate

Eligibility

Sex/Gender

All

Age

14 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. in line with severe traumatic brain injury diagnostic criteria; 2. GCS score 3-8; 3. aged 14-65 years old; 4. no more than 12 hours after brain injury or not more than 6 hours after brain surgery.

Exclusion criteria

Exclusion criteria: 1. pregnant or lactating patients; 2. previous history of serious chronic diseases such as heart, liver and kidney function and severe insufficiency; 3. combined with severe combined injury, hypothermia, etc.; 4. the shock has not been corrected; 5. did not sign the informed consent.

Design outcomes

Primary

Measure	Time frame
REE;ICP;Fatality rat;	—

Countries

China

Contacts

Public ContactFeng Jin-Zhou

Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital

feng720930@gmail.com+86 13688360199

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026