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The effect of dexmedetomidine on laryngeal reflex during recovery in general anesthesia

The effect of dexmedetomidine on laryngeal reflex during recovery in general anesthesia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004208
Enrollment
Unknown
Registered
2014-01-25
Start date
2014-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diseases that need short operations

Interventions

one:dexmedetomidine of 1.0ug/kg+NS 20ml
two:dexmedetomidine of 0.6ug/kg+NS 20ml
three:dexmedetomidine of 0.3ug/kg+NS 20ml
four:NS 20ml

Sponsors

Anesthesiology Department of Zhongshan Hospital Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patient who will accept short operation by general anesthesia without muscle relaxant via a laryngeal mask airway; 2. ASA phisical status I~II; 3. Aged 18 to 70 years; 4. BMI<25kg/m2; 5. Patient who has signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patient who has a history of neuromuscular disorder; 2. Patient who has a history of pharyngeal or upper gastrointestinal surgery; 3. Diabetes; 4. Gastroesophageal reflux; 5. Asthma; 6. Patient who will receive a supraclavicular or interscalene brachial plexus block; 7. Any surgery that will affect the observation of laryngeal reflex; 8. Pregnant woman.

Design outcomes

Primary

MeasureTime frame
the time from stopping anesthetic administration to recovery of laryngeal reflex;the time from stopping anesthetic administration to first response to command;

Secondary

MeasureTime frame
VAS score 30 minutes after recovery;Ramsay score 30 minutes after recovery;QoR-40 score 24h after surgery;

Countries

China

Contacts

Public ContactXue Zhanggang

Zhongshan Hospital Fudan University

xuezgang@aliyun.com+86 13601914601

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026