Breast cancer in females
Conditions
Interventions
Group I:Ultrasound guided multi-level thoracic paravertebral nerve block: In one group, local anesthetic will be injected in all the three levels
while in the other group, local anesthetic will be injected in one thoracic level and saline will be injected subcutaneously or intramuscularly in the other two levels.
Group II:Local anesthetic will be injected in all the three levels
Sponsors
The Chinese University of Hong Kong, Prince of Wales Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: Consenting adult ASA 1-3 patients under the age of 75 years undergoing major breast cancer surgery (which includes axillary lymph node dissection) will be recruited for this study.
Exclusion criteria
Exclusion criteria: The following patients will be excluded from the study: history of chronic pain, history of regular analgesic usage, contraindication to the use of non-steroidal anti-inflammatory drugs (NSAID), known allergy to local anaesthetic drugs, infection at the site of block placement, bleeding tendency or with evidence of coagulopathy, pre-existing neurological or muscular disorders, history of psychiatric illness, pregnant patients, pre-existing nausea or vomiting, patients who received opioid or drugs with antiemetic properties in the 24 h before surgery, patients who received radiotherapy before surgery and patients with breast pain before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute postoperative pain;Analgesic consumption;Quality of Recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of chronic pain;Quality of Life; | — |
Countries
China
Contacts
Public ContactManoj K Karmakar
Prince of Wales Hospital
Outcome results
None listed