premenstrual syndrome
Conditions
Interventions
Experimental :Shu-gan Mianjian granule + fluoxetine
Control :Oral Fluoxetine
Sponsors
Shandong University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. To be diagnosed according to the PMDD Diagnostic criteria in the Diagnostic and Statistical Manual of Mental Disorders 4th Edition (DSM-IV); 2. Aged 18-45 years women, no ethnic limitation; 3. The menstrual cycle of 21-35 days (fluctuation range = 3d); 4. The voluntarily volunteers with the clear consciousness, independent judgment and the ability to understand the purpose of the study; 5. The volunteers without other major mood disorders, brain tumors or other brain disease and history of taking psychotropic medications.
Exclusion criteria
Exclusion criteria: 1. Patients with severe suicidal thoughts or behavior; 2. Patients with loss or lack of ability of independent judgment; 3. Don't understand the purpose of this study or unwilling to cooperate; 4. The depression patients resulted in organic diseases or psychoactive drug substances or nonaddictive substances.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| COR;ACTH;5-HT;NE;BDNF;GABA;Tryptophan;TPH;5-HTPDC;MAO;5-HIAA; | — |
Countries
China
Contacts
Public ContactQiao Mingqi
Shandong University of Traditional Chinese Medicine
Outcome results
None listed