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Effects of dexmedetomidine on immune function in patients of the radical correction of gastric cancer

Effects of dexmedetomidine on immune function and inflammatory response in patients of the radical correction of gastric cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-14004168
Enrollment
Unknown
Registered
2014-01-17
Start date
2014-01-20
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric cancer

Interventions

Control group:normal saline
Experimental:dexmedetomidine

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. patients with the elective radical correction of gastric cancer; 2. ASA Class I or II; 3. Aged 20 to 65 years old, male or female; 4. BMI 20-25kg/m-2.

Exclusion criteria

Exclusion criteria: 1. history of systematic diseases (cardiovascular, brain, pulmonary, kidney or liver diseases), endocrine diseases, tumor diseases; 2. severe hypotension or hypertension; 3. immune system diseases, immunizing drug therapies; 4. a recent history of blood transfusion and infection within one month.

Design outcomes

Primary

MeasureTime frame
helper T cells(Th1/Th2);inflammatory factors (TNF-alpha, IL-6);catecholamin;—

Secondary

MeasureTime frame
circulation system;Ramsay Score;visual analogue scale;—

Countries

China

Contacts

Public ContactFuhai Ji

Department of Anesthesiology, First Affiliated Hospital of Soochow University

jifuhai@hotmail.com+86 13656207331

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026