Childhood obstructive sleep apnoea
Conditions
Interventions
Two groups:Adenotonsillectomy +/- Turbinate reduction vs Watchful waiting 5-6 months latter
Sponsors
Department of Paediatrics, CUHK
Eligibility
Sex/Gender
All
Age
5 Years to 11 Years
Inclusion criteria
Inclusion criteria: (i) Hong Kong Chinese pre-pubertal children aged between 5-11 years; (ii) Moderate-to-severe OSA confirmed by PSG (OAHI > 5); (iii) Tonsil size grading >=1 and considered to be candidates for surgical intervention by ENT surgeon; (iv) Written informed consent obtained from parents.
Exclusion criteria
Exclusion criteria: (i) Obesity, defined as having a body mass index (BMI) >=95th percentile (corresponding to a z score of 1.645) of the local reference; (ii) Previous upper airway surgery or currently receiving treatment for OSA; (iii) Known medical conditions that could affect airway and BP control, for example cranio-facial, neuromuscular diseases and congenital heart disease; (iv) Receiving medications that could alter BP control; (v) Severe health problems that could be exacerbated by delayed treatment of OSA, for example chronic lung disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour ambulatory blood pressure parameter; | — |
Secondary
| Measure | Time frame |
|---|---|
| Polysomnographic indexes, including obstructive apnoea hypopnoea index (OAHI) and respiratory disturbance index (RDI), and symptoms of obstructive sleep apnoea.; | — |
Countries
China
Contacts
Public ContactMr. Au Chun Ting
Department of Paediatrics, Faculty of Medicine, The Chinese University of Hong Kong
Outcome results
None listed