Atorvastatin and BDNF expression in the functional recovery in patients with acute ischemic stroke

The function of BDNF in the recovery following acute ischemic stroke

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-14004120

Enrollment

Unknown

Registered

2014-01-04

Start date

2014-01-15

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ischemic stroke

Interventions

Atorvastatin treated group:Atorvastatin 20mg daily

Atorvastatin untreated group:Placebo daily

Eligibility

Sex/Gender

All

Age

40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients were required to meet the following enrollment criteria: 1. aged 40 to 80 years old; 2. acute onset of stroke within 48 hours and beyond time window for tissue Plasminogen Activator (t-PA) treatment; 3. atherothrombotic subtype of stroke with cortical lesion; 4. and no previous statin use.

Exclusion criteria

Exclusion criteria: Exclusion was based upon patients with any of the following: the presence of some complicated diseases including renal failure, malignancy, thyroid dysfunction and autoimmune disease.

Design outcomes

Primary

Measure	Time frame
serum BDNF;National Institutes of Health Stroke Scale (NIHSS);Modified Rankin Scale (mRS);Barthel Index;	—

Countries

China

Contacts

Public ContactYonglu Huang

The Second Affiliated Hospital of Anhui Medical University

yonglu.huang@gmail.com+86 0551 63869585

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026