Dura splitting decompression versus duraplasty for Chiari I malformation in adult patients: effectiveness, safety and healthcare costs

Dura splitting decompression versus duraplasty for Chiari I malformation in adult patients: effectiveness, safety and healthcare costs-a randomised controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-14004099

Enrollment

Unknown

Registered

2014-01-09

Start date

2014-02-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chiari I malformation

Interventions

A:Dura splitting decompression

B:Duraplasty

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 60 years old; 2. Patients with symptomatic Chiari I malformation did not have surgery for the condition before; 3. Patients accept regular follow-up as required; 4. Patients and their families are informed consent of the study.

Exclusion criteria

Exclusion criteria: 1. Patients with hydrocephalus or atlantoaxial instability; 2. Patients who had posterior cranial fossa decompression or cerebrospinal fluid shunt operation before; 3. Patients with hemorrhagic disease are unable to tolerate surgery; 4. Pregnant patients; 5. Not intend to participate in any clinical trials.

Design outcomes

Secondary

Measure	Time frame
Length of operation;Length of hospital stay;Total costs;Postoperative complications;Postoperative recurrence rate;	—

Primary

Measure	Time frame
Symptom resolution at month 3, 12 post surgery;	—

Countries

China

Contacts

Public ContactSiqing Huang

West China Hospital, Sichuan University

huangsiqing028@163.com+86 18980601507

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 5, 2026