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Therapeutic effect of dependent on remaining GFR calculated for different RRT intensity for AKI: a multi-center, prospective, randomized control study

Therapeutic effect of dependent on remaining GFR calculated for different RRT intensity for AKI: a m

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-13005225
Enrollment
Unknown
Registered
2014-09-21
Start date
2014-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Interventions

lower-intensity group:Remaining eGFR + RRT provided GFR=30ml/min/1.73m2
higher-intensity group:Remaining eGFR + RRT provided GFR=30ml/min/1.73m2

Sponsors

Chinese General Hospital of PLA
Lead Sponsor

Eligibility

Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1.2012 KIDGO clinical practice guideline for acute kidney injury and need blood-purifying therapy; 2.2012 KIDGO AKI definition and 2-3 staging; 3. The remaining eGFR less than 25ml/min/1.73m2; 4.Age older than 18 years, male and female; 5. The initial diagnosis and treatment 6.Patients are expected to be treated for at least 3 days; 7. Complete informed consent form

Exclusion criteria

Exclusion criteria: 1.patients received dialysis before being hospitalized; 2.AKI based on chronic renal failure; 3.simple Pre-renal AKI patients; 4. Post-renal AKI patients; 5. Patients with advanced tumors; 6.Patients with mental illness or can not comply with the treatment because of other reasons; 7. Patients can not tolerate extracorporeal circulation judged the treating clinicians; 8. Renal transplant patients.

Design outcomes

Primary

MeasureTime frame
Routine blood, blood biochemistry, coagulation ind;eGFR, CRP, PCT, IL-6,BNP;Kidney B ultrasound, ECG, chest X-ra;

Countries

China

Contacts

Public ContactXiangmei Chen
xmchen301@126.com+86 10 66935462

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026